Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81358
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dc.contributor.authorWang, Yen_US
dc.contributor.authorLeng, Len_US
dc.contributor.authorIslam, MKen_US
dc.contributor.authorLiu, FHen_US
dc.contributor.authorLin, CSKen_US
dc.contributor.authorLeu, SYen_US
dc.date.accessioned2019-09-20T00:55:10Z-
dc.date.available2019-09-20T00:55:10Z-
dc.date.issued2019-
dc.identifier.citationInternational journal of molecular sciences, 1 July 2019, v. 20, no. 13, 3354, p. 1-17en_US
dc.identifier.issn1661-6596-
dc.identifier.urihttp://hdl.handle.net/10397/81358-
dc.description.abstractCellulosomes are an extracellular supramolecular multienzyme complex that can efficiently degrade cellulose and hemicelluloses in plant cell walls. The structural and unique subunit arrangement of cellulosomes can promote its adhesion to the insoluble substrates, thus providing individual microbial cells with a direct competence in the utilization of cellulosic biomass. Significant progress has been achieved in revealing the structures and functions of cellulosomes, but a knowledge gap still exists in understanding the interaction between cellulosome and lignocellulosic substrate for those derived from biorefinery pretreatment of agricultural crops. The cellulosomic saccharification of lignocellulose is affected by various substrate-related physical and chemical factors, including native (untreated) wood lignin content, the extent of lignin and xylan removal by pretreatment, lignin structure, substrate size, and of course substrate pore surface area or substrate accessibility to cellulose. Herein, we summarize the cellulosome structure, substrate-related factors, and regulatory mechanisms in the host cells. We discuss the latest advances in specific strategies of cellulosome-induced hydrolysis, which can function in the reaction kinetics and the overall progress of biorefineries based on lignocellulosic feedstocks.en_US
dc.description.sponsorshipDepartment of Civil and Environmental Engineeringen_US
dc.language.isoenen_US
dc.publisherMolecular Diversity Preservation International (MDPI)en_US
dc.relation.ispartofInternational journal of molecular sciencesen_US
dc.rights© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.rightsThe following publication Wang, Y.; Leng, L.; Islam, M.K.; Liu, F.; Lin, C.S.K.; Leu, S.-Y. Substrate-Related Factors Affecting Cellulosome-Induced Hydrolysis for Lignocellulose Valorization. Int. J. Mol. Sci. 2019, 20, 3354, 1-17 is available at https://dx.doi.org/10.3390/ijms20133354en_US
dc.subjectCellulosomeen_US
dc.subjectLignocelluloseen_US
dc.subjectSubstrate-related factorsen_US
dc.subjectEnzymatic hydrolysisen_US
dc.subjectBioproductsen_US
dc.subjectReaction kineticsen_US
dc.titleSubstrate-related factors affecting cellulosome-induced hydrolysis for lignocellulose valorizationen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage1-
dc.identifier.epage17-
dc.identifier.volume20-
dc.identifier.issue13-
dc.identifier.doi10.3390/ijms20133354-
dc.identifier.isiWOS:000477041100238-
dc.identifier.scopus2-s2.0-85069304873-
dc.identifier.pmid31288425-
dc.identifier.eissn1422-0067-
dc.identifier.artn3354-
dc.description.validate201909 bcrc-
dc.description.oapublished_final-
Appears in Collections:Journal/Magazine Article
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