Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/80834
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dc.contributor.authorHan, Len_US
dc.contributor.authorRan, JJen_US
dc.contributor.authorMak, YWen_US
dc.contributor.authorSuen, LKPen_US
dc.contributor.authorLee, PHen_US
dc.contributor.authorPeiris, JSMen_US
dc.contributor.authorYang, Len_US
dc.date.accessioned2019-06-13T04:00:12Z-
dc.date.available2019-06-13T04:00:12Z-
dc.date.issued2019-05-
dc.identifier.citationEpidemiology (Philadelphia), May 2019, v. 30, no. 3, p. 405-417en_US
dc.identifier.issn1044-3983en_US
dc.identifier.urihttp://hdl.handle.net/10397/80834-
dc.description.abstractBackground: Although smoking has been recognized as a risk factor for many respiratory diseases, its effects of influenza-associated morbidity and mortality remain controversial. We conducted a systematic review and meta-analysis to assess the impact of smoking on influenza-associated hospital admissions, intensive care unit (ICU) admissions, and deaths.en_US
dc.description.abstractMethods: We searched the databases of PubMed, CINAHL, EMBASE, and the China National Knowledge Infrastructure for all observational studies published between 1 January 2000 and 30 November 2017 on ever-active/secondhand smoking and influenza-associated hospital admissions, ICU admissions, and deaths. We pooled data using random effect models.en_US
dc.description.abstractResults: The initial search retrieved 7495 articles, of which 20 studies were included for systematic review, and 12 studies (eight case–control studies, two cohort studies, and two cross-sectional studies) with 18612 subjects were included in meta-analysis. The overall quality of selected studies was moderate. Ever-active smokers had higher odds of hospital admissions (odds ratio [OR] = 1.5; 95% confidence interval [CI] = 1.3, 1.7) and ICU admissions (OR 2.2; 95% CI = 1.4, 3.4) after influenza infections, as compared with never smokers. No association was observed between ever-active smoking and influenza-associated deaths. We found a positive association between secondhand smoking and influenza-associated hospital admissions, but only in children below 15 years of age.en_US
dc.description.abstractConclusions: The literature evidence showed that smoking was consistently associated with higher risk of hospital admissions after influenza infection, but the results for ICU admissions and deaths were less conclusive because of the limited number of studies.en_US
dc.description.sponsorshipSchool of Nursingen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Healthen_US
dc.relation.ispartofEpidemiology (Philadelphia)en_US
dc.subjectInfluenzaen_US
dc.subjectMeta-analysisen_US
dc.subjectMorbidityen_US
dc.subjectMortalityen_US
dc.subjectSmokingen_US
dc.titleSmoking and influenza-associated morbidity and mortality : a systematic review and meta-analysisen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage405en_US
dc.identifier.epage417en_US
dc.identifier.volume30en_US
dc.identifier.issue3en_US
dc.identifier.doi10.1097/EDE.0000000000000984en_US
dc.identifier.isiWOS:000480682000021c-
dc.identifier.ros2018000159-
dc.identifier.eissn1531-5487en_US
dc.description.validate201906 bcrcen_US
dc.description.oaNot applicableen_US
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