Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/80804
DC Field | Value | Language |
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dc.contributor | Department of Applied Biology and Chemical Technology | - |
dc.creator | Qin, LM | - |
dc.creator | Niu, DC | - |
dc.creator | Jiang, Y | - |
dc.creator | He, JP | - |
dc.creator | Jia, XB | - |
dc.creator | Zhao, WR | - |
dc.creator | Li, P | - |
dc.creator | Li, YS | - |
dc.date.accessioned | 2019-05-28T01:09:31Z | - |
dc.date.available | 2019-05-28T01:09:31Z | - |
dc.identifier.issn | 1176-9114 | - |
dc.identifier.uri | http://hdl.handle.net/10397/80804 | - |
dc.language.iso | en | en_US |
dc.publisher | Dove Medical Press | en_US |
dc.rights | © 2019 Qin et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). | en_US |
dc.rights | The following publication Qin, L. M., Niu, D. C., Jiang, Y., He, J. P., Jia, X. B., Zhao, W. R., ... & Li, Y. S. (2019). Confined growth of multiple gold nanorices in dual-mesoporous silica nanospheres for improved computed tomography imaging and photothermal therapy. International journal of nanomedicine, 14, 1519-1532 is available at https://dx.doi.org/10.2147/IJN.S184192 | en_US |
dc.subject | Gold nanorices | en_US |
dc.subject | Dual-mesoporous silica | en_US |
dc.subject | Confined growth | en_US |
dc.subject | Imaging | en_US |
dc.subject | Photothermal effect | en_US |
dc.title | Confined growth of multiple gold nanorices in dual-mesoporous silica nanospheres for improved computed tomography imaging and photothermal therapy | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 1519 | - |
dc.identifier.epage | 1532 | - |
dc.identifier.volume | 14 | - |
dc.identifier.doi | 10.2147/IJN.S184192 | - |
dcterms.abstract | Introduction: In this work, we have developed a novel "confined-growth" strategy to synthesize PEGylated multiple gold nanorices-encapsulated dual-mesoporous silica nanospheres (designated as PEGylated MGNRs@DMSSs) containing both small mesopores (2.5 nm) in the shell and large mesopores (21.7 nm) in the core based on a well-established, seed-mediated growth method. The photothermal effect and CT imaging ability were also studied. | - |
dcterms.abstract | Methods: The nanoparticles were characterized by Fourier transform infrared (FT-IR) spectra, N-2 absorption isotherms, Field-emission scanning electron microscopy (FE-SEM), Transmission electron microscopy (TEM), Inductively coupled plasma atomic emission spectroscopy (ICP-AES) and Confocal microscopy. | - |
dcterms.abstract | Results: The longitudinally-localized surface (LSPR) absorption properties of MGNRs@DMSSs can be easily tuned by altering the amount of HAuCl4 in the gold growth solution. Additionally, the resultant PEGylated MGNRs@DMSSs have monodispersed, spherical morphology and good colloidal stability in an aqueous solution. More importantly, when exposed to NIR irradiation, the PEGylated MGNRs@DMSSs exhibit both higher temperature increments and better photothermal effects than that of single PEGylated gold nanorods at nearly an equivalent LSPR absorption. In addition, as CT contrast agents, the PEGylated MGNRs@DMSSs display a better CT imaging performance, in comparison with single PEGylated gold nanorods at the same Au concentration. | - |
dcterms.abstract | Conclusion: Taken together, results indicate the potential for MGNRs@DMSSs used in CT imaging-guided photothermal therapy. Such a simple "confined-growth" strategy within a porous matrix offers a promising platform to design and prepare novel metal(s) oxide@silica nanocomposites for use in further cancer bio-imaging and therapy. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | International journal of nanomedicine, 2019, v. 14, p. 1519-1532 | - |
dcterms.isPartOf | International journal of nanomedicine | - |
dcterms.issued | 2019 | - |
dc.identifier.isi | WOS:000460049700004 | - |
dc.identifier.pmid | 30880962 | - |
dc.identifier.eissn | 1178-2013 | - |
dc.description.validate | 201905 bcrc | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
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File | Description | Size | Format | |
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Qin_Confined_Gold_Dual-mesoporous.pdf | 5.6 MB | Adobe PDF | View/Open |
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