Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/79746
Title: New secoiridoids from the fruits of ligustrum lucidum
Authors: Qiu, ZC
Zhao, XX
Wu, QC
Fu, JW
Dai, Y
Wong, MS 
Yao, XS
Keywords: Oleaceae
Secoiridoids
Ligustri lucidi fructus
MC3T3-E1 cells
Osteogenic activity
Issue Date: 2018
Publisher: Harwood Academic Publishers
Source: Journal of Asian natural products research, 2018, v. 20, no. 5, p. 431-438 How to cite?
Journal: Journal of Asian natural products research 
Abstract: Three new secoiridoids, nuezhenelenoliciside (1), isojaslanceoside B (2), 6-O-trans-cinnamoyl-secologanoside (3), were isolated from the dried fruits of Ligustrum lucidum. Their structures were elucidated by comprehensive spectroscopic analysis. Among them, 1 featured a rare rearrangement product of secoiridoid, which underwent the cleavage of chemical bond between C-1 and O-2, and the reformation of a new iridoid ring between C-8 and O-2. In addition, all compounds were tested for their osteogenic activity on pre-osteoblastic MC3T3-E1 cells. As a result, 1 and 3 exhibited potent effects on promoting cell proliferation of pre-osteoblast cells. [GRAPHICS] .
URI: http://hdl.handle.net/10397/79746
EISSN: 1028-6020
DOI: 10.1080/10286020.2018.1454438
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