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Title: Cosmetic and skincare benefits of cultivated mycelia from the Chinese caterpillar mushroom, ophiocordyceps sinensis (Ascomycetes)
Authors: Cheng, WY 
Wei, XQ 
Siu, KC 
Song, AX 
Wu, JY 
Keywords: Anticollagenase
Cordyceps sinensis
Medicinal mushrooms and fungi
Mycelial extract
Ophiocordyceps sinensis
Issue Date: 2018
Publisher: Begell House
Source: International journal of medicinal mushrooms, 2018, v. 20, no. 7, p. 623-636 How to cite?
Journal: International journal of medicinal mushrooms 
Abstract: Mushrooms are potential sources of novel natural cosmeceutical ingredients. This study was conducted to evaluate the cosmetic (skincare) benefits of the valuable medicinal species Ophiocordyceps sinensis (=Cordyceps sinensis). The mycelial extracts of 2 O. sinensis strains, Cs-HKl and Cs-4, prepared sequentially with ethyl acetate, ethanol, and hot water were tested with in vitro assays for tyrosinase-, collagenase-, and elastase-inhibitory activity. The ethyl acetate extracts of both fungal strains showed potent antityrosinase and antielastase activity, with low half-maximal inhibitory concentrations (0.14-0.47 mg/mL) comparable to those of the respective reference compounds (arbutin and epigallocatechin gallate). All mycelial extracts exhibited moderate or significant anticollagenase activity; most extracts showed a significant photoprotective effect with a sun protection factor up to 25. The results from this study show the potential use of O. sinensis as a source of cosmetic ingredients for skincare applications.
ISSN: 1521-9437
EISSN: 1940-4344
DOI: 10.1615/IntJMedMushrooms.2018026883
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