Quinoline derivatives as anti-cancer agents

Abstract

Quinoline derivatives showing anticancer activities against cancer cell lines of hepatocellular carcinoma (Hep3B), lung carcinoma (A549), esophageal squamous cell carcinoma (HKESC-1, HKESC-4 and KYSE150). The quinoline derivatives have a backbone structure of the following formulas. 喹啉衍生物，所述喹啉衍生物显示出抗肝细胞癌(Hep3B)、肺癌(A549)、食管鳞细胞癌(HKESC‑1、HKESC‑4和KYSE150)的癌细胞系的抗癌活性。所述喹啉衍生物具有以下式子的骨架结构。