Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/76359
Title: An efficient nickel-catalyzed asymmetric oxazole-forming Ugi-type reaction for the synthesis of chiral aryl-substituted THIQ rings
Authors: Li, D
Yang, DX
Wang, LQ
Liu, XH
Wang, KZ
Wang, J
Wang, PX
Liu, YY
Zhu, HY
Wang, R 
Keywords: Chirality
Nickel
Oxazole
Tetrahydroquinoline
Ugi reaction
Issue Date: 2017
Publisher: Wiley-VCH
Source: Chemistry - a European journal, 2017, v. 23, no. 29, p. 6974-6978 How to cite?
Journal: Chemistry - a European journal 
Abstract: A nickel-catalyzed asymmetric oxazole-forming Ugi reaction of C,N-cyclic azomethine imines and isonitriles is disclosed. The reported protocol proceeds smoothly, and gives the corresponding adducts, which contain two important pharmaceutically active ring-systems (tetrahydroquinoline and oxazole rings), in good yields and excellent enantioselectivities by employing an easily accessible chiral diamine as a ligand. This simple and efficient strategy provides easy access to a series of C1-substituted aryl tetrahydroisoquinolines.
URI: http://hdl.handle.net/10397/76359
ISSN: 0947-6539
EISSN: 1521-3765
DOI: 10.1002/chem.201700970
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

3
Citations as of Dec 7, 2018

WEB OF SCIENCETM
Citations

2
Last Week
0
Last month
Citations as of Dec 13, 2018

Page view(s)

23
Citations as of Dec 17, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.