Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/76293
Title: A Palladium-catalyzed alpha-arylation of Oxindoles with Aryl Tosylates
Authors: Duan, JD 
Kwong, FY 
Issue Date: 2017
Publisher: American Chemical Society
Source: Journal of organic chemistry, 2017, v. 82, no. 12, p. 6468-6473 How to cite?
Journal: Journal of organic chemistry 
Abstract: A palladium-catalyzed monoselective C3 arylation of 2-oxindoles with aryl tosylates is described. With the Pd/CM-phos catalyst system, the corresponding 3-arylated oxindoles can be obtained in good to excellent yields (<= 97%). The reaction conditions are mild (using 0.5 mol % Pd in general and KF as a base), and functional groups such as methyl ester, NH amido, and enolizable keto moieties are found to be compatible.
URI: http://hdl.handle.net/10397/76293
ISSN: 0022-3263
EISSN: 1520-6904
DOI: 10.1021/acs.joc.7b00855
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