Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/75492
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dc.contributorDepartment of Biomedical Engineering-
dc.creatorZhou, B-
dc.creatorLeung, BYK-
dc.creatorSun, L-
dc.date.accessioned2018-04-27T01:31:41Z-
dc.date.available2018-04-27T01:31:41Z-
dc.identifier.issn2314-6133en_US
dc.identifier.urihttp://hdl.handle.net/10397/75492-
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.rightsCopyright © 2017 Bill Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rightsThe following article: Bill Zhou, Benny Yuk Kin Leung, and Lei Sun, “The Effects of Low-Intensity Ultrasound on Fat Reduction of Rat Model,” BioMed Research International, vol. 2017, Article ID 4701481, 8 pages, 2017 is available at https://doi.org/10.1155/2017/4701481.en_US
dc.titleThe effects of low-intensity ultrasound on fat reduction of rat modelen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.volume2017en_US
dc.identifier.doi10.1155/2017/4701481en_US
dcterms.abstractNonfocused low-intensity ultrasound is generally believed to be less efficacious than High-Intensity Focused Ultrasound (HIFU) at body fat reduction; nevertheless, this technology has already been widely used clinically for body contouring purposes. This study aimed to evaluate the efficacy and safety of this new technology by applying 1 MHz nonfocused ultrasound at 3 W/cm2 to the outer-thigh region of rat models. Ultrasonography measurement demonstrated an average reduction of 0.5 mm of subcutaneous fat thickness that persisted for at least three days after treatment. Biochemical analysis quantified a significant increase in lipid levels, specifically triglyceride, high-density lipoprotein, and total cholesterol. These two findings of subcutaneous fat reduction and plasma lipid increase showed a positive correlation. No evidence of adverse events or complications was observed after the treatment. This study validated nonfocused low-intensity ultrasound as an effective and safe method for body fat reduction, especially with repetitive treatment. However, the concurrent increase in plasma lipid level will require further investigation to determine this technology's long-term impact, if any, on health.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationBioMed research international, 2017, v. 2017, 4701481-
dcterms.isPartOfBioMed research international-
dcterms.issued2017-
dc.identifier.isiWOS:000408231200001-
dc.identifier.scopus2-s2.0-85029171753-
dc.identifier.ros2016002134-
dc.identifier.eissn2314-6141en_US
dc.identifier.artn4701481en_US
dc.identifier.rosgroupid2016002090-
dc.description.ros2016-2017 > Academic research: refereed > Publication in refereed journalen_US
dc.description.validate201811_a bcmaen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_IR/PIRAen_US
dc.description.pubStatusPublisheden_US
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