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Title: Rapid detection of drugs-of-abuse in urine and oral fluid by mass spectrometry
Authors: Ng, TT 
Hu, B 
So, PK 
Yao, ZP 
Keywords: Ambient inoization
Drug analysis
Solid phase microextraction
Wooden-tip electrospray ionization mass spectrometry
Issue Date: 2017
Publisher: TechConnect
Source: TechConnect briefs. Volume 3: Biotech, biomaterials and biomedical, 2017, p. 261-263 How to cite?
Journal: TechConnect briefs. Volume 3: Biotech, biomaterials and biomedical 
Abstract: Development of simple, reliable and cost-effective methods for drug analysis is crucial for the fight against drug abuse. In order to deal with large number of samples, preliminary screening is normally firstly applied, followed by confirmatory analysis. However, the preliminary screening, which involves the use of testing kits, has the problem of producing false positive or false negative results, while the confirmatory analysis is time-consuming and laborious as extensive sample pretreatment and chromatographic separation process are required. To solve these problems, we have developed two techniques, i.e., wooden-tip electrospray ionization mass spectrometry (WT-ESI-MS) and solid phase microextraction coupled with electrospray ionization mass spectrometry (SPME-ESI-MS), for rapid and reliable detection of common drugs-of-abuse in human urine and oral fluid.
Description: 11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference, 14 - 17 May 2017
ISBN: 9780998878201
Appears in Collections:Conference Paper

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