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Title: Microarray and fluidic chip for extracellular sensing
Authors: Ozkan, M
Ozkan, C 
Prasad, S
Yang, M 
Zhang, X 
Keywords: Permeability
Issue Date: 2006
Publisher: Springer
Source: In F Mauro (Ed.), BioMEMS and biomedical nanotechnology. Vol. 2 Micro/nano technology for genomics and proteomics, p.47-102. New York: Springer, 2006 How to cite?
Abstract: In the past two decades, the biological and medical fields have seen great advances in the development of biosensors and biochips capable of characterizing and quantifying biomolecules. Biosensors incorporate a biological sensing element that converts a change in an immediate environment to signals conducive for processing. Biosensors have been implemented for a number of applications ranging from environmental pollutant detection to defense monitoring. This chapter first provides an overview of the various types of biosensors and biochips that have been developed for biological applications, along with significant advances over the last several years in these technologies. It also describes the various classification schemes that can be used for categorizing the different biosensors and provides relevant examples of these classification schemes from recent literature. Finally it elucidates a sensing scheme based on cell based sensors. This technique is based on the development of single cell arrays that are used as biosensors that show parts per billion sensitivity and have the capability of identifying specific chemical analytes based on unique electrical identification tags also known as “Signature Patterns”. The reliability of this technique is verified using conventional fluorescence based techniques.
ISBN: 9780387258430 (v. 2 : ebk.)
9780387255644 (v. 2)
0387255648 (v. 2)
DOI: 10.1007/978-0-387-25843-0_3
Appears in Collections:Book Chapter

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