Keratin-peptide-modified polyethylene glycol hydrogel, and preparation method and application thereof

Abstract

The invention discloses a keratin-peptide-modified polyethylene glycol hydrogel, and a preparation method and an application thereof. The keratin-peptide-modified polyethylene glycol hydrogel comprises a copolymer of keratin-peptide-modified polyethylene glycol and polyethylene glycol acrylate monomer. According to the keratin-peptide-modified polyethylene glycol hydrogel provided by the invention, with the good biological performances of natural keratin peptide and the fine regulation capacity of polyethylene glycol hydrogel, the bio-functional material hydrogel product with promotion function upon cell adhesion and growth is obtained. 本发明公开了一种角蛋白肽修饰的聚乙二醇水凝胶，以及其制备方法与应用。所述角蛋白肽修饰的聚乙二醇水凝胶包括角蛋白肽修饰的聚乙二醇与聚乙二醇丙烯酸酯类单体共聚物。本发明公开的角蛋白肽修饰的聚乙二醇水凝胶利用天然角蛋白肽的良好生物性能和聚乙二醇水凝胶的可精细调控能力，得到对细胞黏附和生长的有促进作用的生物功能材料水凝胶产品。