Microneedles array, die casting method for manufacturing microneedle array and die for manufacturing microneedle array

Abstract

The invention provides a microneedles array, a method for manufacturing the microneedles array and a die for manufacturing the microneedles array. The microneedles array comprises a base and a plurality of microneedles which are integrated with the base, wherein a liquid storage cavity is arranged in the base, and each microneedle are provided with micro-pinholes which are communicated with the liquid storage cavity; the microneedles array is made of plastics, composite materials, and ceramics or metal materials by injection molding; and each microneedle has at least one inclined surface which is inclined towards the central line of the microneedle, and the outlet of each micro-pinhole is positioned on at least one inclined surface, so that the end of the outlet of the microneedle forms apinnacle part. The die specialized for the invention comprises an upper die, a middle die and a lower die, wherein the middle die and the lower die are provided with cavities for forming the microneedles; and the upper die and the middle die are provided with grooves for forming the base. The three-plate die of the invention can be used for conveniently manufacturing the microneedles array with the pinnacles. Since the stripping process in the injection molding method using three layers of die comprising the upper die, middle die and lower die, the method has the advantages of small die drawing resistance and low manufacturing cost. 本发明提供了一种微针阵列、制造该种微针阵列的方法及其使用的模具。微针阵列包括基座和与基座一体成型的若干个微针。基座内设有储液腔，每个微针内具有与储液腔连通的微针孔。微针阵列由塑料、复合材料、陶瓷或金属材料经注射成型工艺制成。每个微针上具有至少一个倾斜于微针中心线的斜面，微针孔的出口位于至少一个斜面上，这样在微针的出口端部形成尖峰部分。本发明的专用模具包括上模、中模和下模，中模和下模上设有用于形成微针的空穴，上模和中模上设有用于形成基座的凹槽。使用本发明的三板模具可方便制造出带有尖峰的微针阵列。本发明由于使用上模、中模、下模三层模具，所以拔模阻力小，制造成本低。