Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/68488
Title: Pleurotus tuber-regium polysaccharide functionalized nano-selenium hydrosol with anti-tumor activity and preparation method thereof
Authors: Chen, TF
Wong, KH 
Wu, HL
Zheng, WJ
Wong, MK 
Man, WYC 
Issue Date: 7-Jul-2015
Source: US Patent 9,072,669 B2. Washington, DC: US Patent and Trademark Office, 2015. How to cite?
Abstract: The preparation of Pleurotus tuber-regium polysaccharide functionalized nano-selenium hydrosol with anti-tumor activity includes the following steps: 1) at normal temperature and under normal pressure, adding a Vitamin C solution to an aqueous solution of Pleurotus tuber-regium polysaccharides, and mixing uniformly; 2) adding dropwise a selenium dioxide solution or a selenite solution to the solution while mixing uniformly; and 3) adding water to the solution to a pre-determined volume, to obtain a Pleurotus tuber-regium polysaccharide functionalized nano-selenium hydrosol when the red color of the product is no longer deepened. The polysaccharides are used to control the particle size of nano-selenium, to obtain functionalized nano-elemental selenium with high anti-tumor activity and low toxicity. The anti-tumor activity of the biologically active molecule polysaccharides and the physiological effect of nano-selenium are combined, and a synergistic anti-tumor effect is achieved.
URI: http://hdl.handle.net/10397/68488
Rights: Assignee: The Hong Kong Polytechnic Univeristy.
Appears in Collections:Patent

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