Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/66734
Title: Direct analysis of traditional Chinese medicines by mass spectrometry
Authors: Wong, MYM 
So, PK 
Yao, ZP 
Keywords: Traditional Chinese medicines
Mass spectrometry
Direct analysis
Ambient ionization
Matrix-assisted laser desorption/ionization
Issue Date: 2016
Publisher: Elsevier
Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 15 Jul. 2016, v. 1026, p. 2-14 How to cite?
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 
Abstract: Analysis of traditional Chinese medicines (TCMs) plays important roles in quality control of TCMs and understanding their pharmacological effects. Mass spectrometry (MS) is a technique of choice for analysis of TCMs due to its superiority in speed, sensitivity and specificity. However, conventional MS analysis of TCMs typically requires extensive sample pretreatment and chromatographic separation, which could be time-consuming and laborious, prior to the analysis. The expanding usage of TCMs worldwide demands development of rapid, cost-effective and reliable methods for analysis of TCMs. In recent years, new sample preparation and ionization techniques have been developed to enable direct analysis of TCMs by MS, significantly reducing the analysis time and cost. In this review, various MS-based techniques, mainly including ambient ionization-MS and MALDI-MS based techniques, applied for direct analysis of TCMs are summarized and their applicability and future prospects are discussed.
URI: http://hdl.handle.net/10397/66734
ISSN: 1570-0232
DOI: 10.1016/j.jchromb.2015.11.032
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