Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/65981
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dc.contributorDepartment of Rehabilitation Sciencesen_US
dc.creatorChan, SCCen_US
dc.creatorLam, TLHen_US
dc.creatorFong, KNKen_US
dc.creatorPang, MYCen_US
dc.creatorChan, CCHen_US
dc.date.accessioned2017-05-22T02:09:31Z-
dc.date.available2017-05-22T02:09:31Z-
dc.identifier.issn1664-5464en_US
dc.identifier.urihttp://hdl.handle.net/10397/65981-
dc.language.isoenen_US
dc.publisherS. Karger AGen_US
dc.rights© 2016 The Author(s)en_US
dc.rightsThis article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Interna-tional License (CC BY-NC-ND) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribu-tion for commercial purposes as well as any distribution of modified material requires written permission.en_US
dc.subjectEvent-related potentialen_US
dc.subjectGeneralization of context-specific trainingen_US
dc.subjectMild cognitive impairmenten_US
dc.subjectN200en_US
dc.subjectP300en_US
dc.subjectWorking memoryen_US
dc.titleGeneralization of context-specific training in individuals with mild cognitive impairment : an event-related potential studyen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage568en_US
dc.identifier.epage579en_US
dc.identifier.volume6en_US
dc.identifier.issue3en_US
dc.identifier.doi10.1159/000453546en_US
dcterms.abstractBackground: This study examined the neural processes associated with the generalization of the effect of context-specific (CS) training to noncontextual situations among individuals with mild cognitive impairment (MCI).en_US
dcterms.abstractMethods: Fourteen and 16 participants with MCI were randomly allocated to a Chinese calligraphy writing (CW) training or a control group, respectively. The CW participants learned how to write Chinese strokes in a semicursive style to construct characters, tapping on working memory functions. The control group, on the other hand, learned how to use a tablet computer without emphasis on working memory functions. They then performed two 2-back tasks with CS semicursive strokes and non-context-specific (NCS) digits. Event-related electroencephalogram signals were concurrently recorded.en_US
dcterms.abstractResults: The CW participants had a significantly shorter reaction time in the CS than in the NCS task (p < 0.05). They showed significantly longer latency in working memory updating (N200; t11 = 4.70, p = 0.05) and shorter latency in the evaluation of visual representation (P300; t12 = 4.67; p = 0.05) than the control group when performing the 2-back CS task. Shorter P300 latency was also revealed in the 2-back NCS task (t12 = 5.15, p = 0.041), suggesting a possible generalization of the training effect among the CW participants.en_US
dcterms.abstractConclusion: The results suggest that CS working memory is likely to be generalized to NCS domains among individuals with MCI. Future research should extend the scope of the generalization and apply it beyond experimental conditions.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationDementia and geriatric cognitive disorders extra, Sept. – Dec. 2016, v. 6, no. 3, p. 568-579en_US
dcterms.isPartOfDementia and geriatric cognitive disorders extraen_US
dcterms.issued2016-09-
dc.identifier.scopus2-s2.0-85009751169-
dc.identifier.ros2016001905-
dc.identifier.rosgroupid2016001869-
dc.description.ros2016-2017 > Academic research: refereed > Publication in refereed journalen_US
dc.description.validate201804_a bcmaen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumbera0590-n20, a0729-n63, a0803-n07, a0821-n01-
dc.identifier.SubFormID344, 1289, 1825, 2045-
dc.description.fundingSourceOthersen_US
dc.description.fundingTextHMRF 09101331 (Ref: 1289 [a0729-n63]), P0012187 (Ref: 2045 [a0803-n07])en_US
dc.description.pubStatusPublisheden_US
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