Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/65942
Title: High performance shape memory foams with isocyanate-modified hydroxyapatite nanoparticles for minimally invasive bone regeneration
Authors: Xie, R 
Hu, JL 
Ng, MCF 
Tan, L 
Qin, T
Zhang, M
Guo, X 
Keywords: Composites
Mechanical properties
Thermomechanical properties
Isocyanate-modified hydroxyapatite
Issue Date: 2017
Publisher: Pergamon Press
Source: Ceramics international, 2017, v. 43, no. 6, p. 4794-4802 How to cite?
Journal: Ceramics international 
Abstract: This study conducts a comprehensive assessment of shape memory polyurethane (SMPU) composite foams with isocyanate-modified hydroxyapatite (imHA) nanoparticles in terms of their pore structures, mechanical properties, shape memory effects and biocompatibility in vitro. The results obtained in the research reveal the effectiveness of imHA nanoparticles in SMPU foams as inorganic cross-linking fillers, which contribute to the enhancement of mechanical properties and shape memory performance. Pore structures and compressive properties are simultaneously optimized when imHA content increases. The imHA enhanced SMPU foam could be adopted as a promising alternative for overcoming the disadvantages of traditional polymer scaffolds, such as insufficient mechanical properties, inadequate pore structure, low bioactivity and inconvenience in operation for bone regeneration.
URI: http://hdl.handle.net/10397/65942
ISSN: 0272-8842
EISSN: 1873-3956
DOI: 10.1016/j.ceramint.2016.11.216
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