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Title: Effect of multipurpose solutions on in vivo surface wettability of a silicone hydrogel lens
Authors: Lau, JKK
So, HT
Chiang, TK
Cho, P
Keywords: Multipurpose solution
Silicone hydrogel
Issue Date: 2016
Publisher: Elsevier
Source: Contact lens and anterior eye, 2016, v. 39, no. 6, p. 461-465 How to cite?
Journal: Contact lens and anterior eye 
Abstract: Purpose To compare the in vivo surface wettability of silicone hydrogel (SiHy) contact lenses pre-soaked overnight in different multipurpose solutions (MPS) and normal saline. Methods In this double-blinded, randomized and self-controlled study, 36 subjects were fitted with three pairs of contact lenses (senofilcon A) pre-soaked overnight in five different MPS and saline in a randomized order. Each pair of lenses (pre-soaked in two different solutions the night before) were worn for 15 min before assessment of pre-lens non-invasive tear break-up time (PL-NITBUT) using the Medmont corneal topographer (video recording). Corneal integrity was assessed using a slit lamp and a resting interval of 20 min was allowed between each pair of lenses to ensure post-lens wear corneal integrity. Results Thirty subjects completed the study. The median PL-NITBUT ranged from 2.84 s to 3.08 s with lenses pre-soaked in different MPS, compared to 2.78 s with lenses pre-soaked in saline. No significant differences in PL-NITBUT were found among lenses pre-soaked in different solutions (p = 0.647). Conclusion In vivo surface wettability, in terms of PL-NITBUT after 15 min of lens wear, of senofilcon A contact lenses pre-soaked overnight in different MPS were not significantly different from those pre-soaked in saline.
ISSN: 1367-0484
EISSN: 1476-5411
DOI: 10.1016/j.clae.2016.07.001
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