Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/63997
| DC Field | Value | Language |
|---|---|---|
| dc.contributor | Department of Applied Biology and Chemical Technology | - |
| dc.creator | Wan, ZM | - |
| dc.creator | Bao, SY | - |
| dc.creator | Qian, ZM | - |
| dc.date.accessioned | 2017-02-09T08:32:52Z | - |
| dc.date.available | 2017-02-09T08:32:52Z | - |
| dc.identifier.issn | 1673-4165 | - |
| dc.identifier.uri | http://hdl.handle.net/10397/63997 | - |
| dc.language.iso | zh | en_US |
| dc.publisher | 该杂志社 | en_US |
| dc.rights | © 2004 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。 | en_US |
| dc.rights | © 2004 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research purposes. | en_US |
| dc.subject | Transferrin | en_US |
| dc.subject | Cerebral infarction | en_US |
| dc.subject | Blood-brain barrier | en_US |
| dc.subject | Monoclonal antibodies | en_US |
| dc.title | Application of the transferrin receptor-mediated drug delivery systems in the treatment of acute cerebral infarction | en_US |
| dc.type | Journal/Magazine Article | en_US |
| dc.identifier.spage | 301 | - |
| dc.identifier.epage | 303 | - |
| dc.identifier.volume | 12 | - |
| dc.identifier.issue | 4 | - |
| dcterms.abstract | 在急性脑缺血的超早期,完整的血脑屏障(BBB)使许多治疗药物无法在有效治疗时间窗内进入脑组织发挥作用。转铁蛋白受体(TfR)单克隆抗体能有效通过受体介导的细胞内吞作用使结合的药物通过BBB,从而大大增加了治疗药物的定向选择性,使之更好地发挥治疗作用。 | - |
| dcterms.abstract | In the super early phase of acute cerebral ischemia, many therapeutic drugs cannot penetrate into the complete blood-brain barrier (BBB) and enter brain tissues within the effective time window. The transferrin receptor(TfR) monoclonal antibodies can effectively penetrate BBB via receptor-mediated endocytosis and make the combined drugs penetrate BBB, and thus increasing the orientation selectivity of the therapeutic drugs considerably, and developing their better therapeutic effect. | - |
| dcterms.accessRights | open access | en_US |
| dcterms.alternative | 转铁蛋白受体介导的药物转运在急性脑梗死治疗中的应用 | - |
| dcterms.bibliographicCitation | 国外医学. 脑血管疾病分册 (Cerebrovascular diseases foreign medical sciences), 2004, v. 12, no. 4, p. 301-303 | - |
| dcterms.isPartOf | 国外医学. 脑血管疾病分册 (Cerebrovascular diseases foreign medical sciences) | - |
| dcterms.issued | 2004 | - |
| dc.identifier.rosgroupid | r20907 | - |
| dc.description.ros | 2004-2005 > Academic research: refereed > Publication in refereed journal | - |
| dc.description.oa | Version of Record | en_US |
| dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
| dc.description.pubStatus | Published | en_US |
| Appears in Collections: | Journal/Magazine Article | |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| r20907.pdf | 265.14 kB | Adobe PDF | View/Open |
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