Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/6313
Title: Method of biosynthesizing tetrodotoxin
Other Titles: 河豚毒素的生物合成方法
Authors: Yu, PH
Yu, FC
Issue Date: 14-Aug-2013
Publisher: 中华人民共和国国家知识产权局
Source: 中国专利 ZL 200880005935.1 How to cite?
Abstract: The present invention relates methods for the biosynthesis of tetrodotoxin (TTX) involving the steps of obtaining a culture possessing one or more of a Vibrio species, such as through a seed culture/ inoculating the culture and tissue extract from a textrodotoxin-bearing organism in a fermenter medium, and isolating and purifying tetrodotoxin from said fermenter, resulting in a yield of TTX of about 0.5 g TTX/L in about 3 to 5 days, such TTX being at least 90% pure.
本发明涉及河豚毒素的生物合成方法,包括获取具有一种或多种弧菌的培养,如通过种菌培养;将弧菌培养和产生TTX有机体的组织提取物加入发酵器中的培养基中;和从所述发酵器分离纯化TTX。本发明的方法在约3-5天的时间得到大约0.5mg/L的TTX产出,TTX的纯度至少为90%。
URI: http://hdl.handle.net/10397/6313
Rights: 专利权人: The Hong Kong Polytechnic University.
Appears in Collections:Patent

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