Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/62212
Title: Heterogeneous phase transfer catalysis in solid phase syntheses of anth-cyclic tetrapeptides
Authors: Xin, D
Yuan, J
Wong, KY 
Burgess, K
Issue Date: 2016
Publisher: American Chemical Society
Source: Journal of organic chemistry, 2016, v. 81, no. 17, p. 8077-8081 How to cite?
Journal: Journal of organic chemistry 
Abstract: This study features solid phase syntheses of cyclic tetrapeptides containing anthranilic acid (Anth) on relatively inexpensive resins derived from polystyrene. It proved to be difficult to hydrolyze a supported Anth-methyl ester unless a phase transfer catalyst was added to facilitate transport of hydroxide into the swollen hydrophobic gel state of the resin. We suggest this may be an under-appreciated strategy for improving syntheses on polystyrene supports.
URI: http://hdl.handle.net/10397/62212
ISSN: 0022-3263
EISSN: 1520-6904
DOI: 10.1021/acs.joc.6b01475
Appears in Collections:Journal/Magazine Article

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