Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/62139
Title: Laser fabrication of Ag-HA nanocomposites on Ti6Al4V implant for enhancing bioactivity and antibacterial capability
Authors: Liu, X
Man, HC 
Keywords: Ag-HA
Antibacterial
Cytocompatibility
Laser processing
Nanocomposite
Titanium implant
Issue Date: 2017
Publisher: Elsevier
Source: Materials science and engineering. C, materials for biological applications, 2017, v. 70, p. 1-8 How to cite?
Journal: Materials science and engineering. C, materials for biological applications 
Abstract: For titanium alloy implants, both surface bioactivity and antibacterial infection are the two critical factors in determining the success of clinical implantation of these metallic implants. In the present work, a novel nanocomposite layer of nano-silver-containing hydroxyapatite (Ag-HA) was prepared on the surface of biomedical Ti6Al4V by laser processing. Analysis using SEM, EDS and XRD shows the formation of an Ag-HA layer of about 200 μm fusion bonded to the substrate. Mineralization tests in simulated body fluid (SBF) showed that laser fabricated Ag-HA nanocomposite layer favors the deposition of apatite on the surface of the implants. Antibacterial tests confirmed that all Ag-HA nanocomposite layers can kill bacteria while a higher Ag content would lower the cytocompatibility of these coatings. Cell viability decreases when the Ag content reaches 5% in these coatings, due to the larger amount of Ag leached out, as confirmed by ion release evaluation. Our results reveal that laser fabricated Ag-HA nanocomposite coatings containing 2% Ag show both excellent cytocompatibility and antibacterial capability.
URI: http://hdl.handle.net/10397/62139
ISSN: 0928-4931
DOI: 10.1016/j.msec.2016.08.059
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