Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/609
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | - |
dc.creator | Wong, KY | - |
dc.creator | Leung, TYC | - |
dc.creator | Chan, PH | - |
dc.date.accessioned | 2009-02-10T10:04:47Z | - |
dc.date.available | 2009-02-10T10:04:47Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/609 | - |
dc.language.iso | en | en_US |
dc.rights | Assignee: The Hong Kong Polytechnic University. | en_US |
dc.subject | β-lactamases | en_US |
dc.title | Modified β-lactamases and uses thereof | en_US |
dc.type | Patent | en_US |
dc.description.otherinformation | US7323303; US7323303 B2; US7323303B2; US7,323,303; US7,323,303 B2; 7323303; Application No. 10/401,867 | en_US |
dc.description.otherinformation | Inventor name used in this publication: Thomas Yun-Chung Leung | en_US |
dc.description.otherinformation | Inventor name used in this publication: Pak-Ho Chan | en_US |
dcterms.abstract | A tool that can screen bacteria for β-lactamases against a panel of various antibiotics is desirable. A biosensor incorporating an indicator molecule into β-lactamases may achieve this purpose, but it requires that the attached indicator molecule must not impair the binding affinity of the protein to a great extent to provide a higher sensitivity. A modified β-lactamases with a residue on the Ω-loop or outside the Ω-loop but close to the active site of β-lactamase being replaced by a reactive residue is developed in this invention. | - |
dcterms.bibliographicCitation | US Patent 7,323,303 B2. Washington, DC: US Patent and Trademark Office, 2008. | - |
dcterms.issued | 2008-01-29 | - |
dc.description.country | US | - |
dc.description.oa | Version of Record | en_US |
Appears in Collections: | Patent |
Files in This Item:
File | Description | Size | Format | |
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us7323303b2.pdf | 1.15 MB | Adobe PDF | View/Open |
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