Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/60865
Title: Mushroom-derived preparations in the prevention of H2O2-induced oxidative damage to cellular DNA
Authors: Shi, YL
James, AE
Benzie, IFF 
Buswell, JA
Issue Date: 2002
Publisher: Wiley
Source: Teratogenesis carcinogenesis and mutagenesis, 2002, v. 22, no. 2, p. 103-111 How to cite?
Journal: Teratogenesis carcinogenesis and mutagenesis 
Abstract: Aqueous extracts of the sporophores of eight mushroom species were assessed for their ability to prevent H2O2-induced oxidative damage to cellular DNA using the single-cell gel electrophoresis (“Comet”) assay. The highest genoprotective effects were obtained with cold (20°C) and hot (100°C) water extracts of Agaricus bisporus and Ganoderma lucidum fruit bodies, respectively. No protective effects were observed with Mushroom Derived Preparations (MDPs) from Flammulina velutipes, Auricularia auricula, Hypsizygus marmoreus, Lentinula edodes, Pleurotus sajor-caju, and Volvariella volvacea. These findings indicate that some edible mushrooms represent a valuable source of biologically active compounds with potential for protecting cellular DNA from oxidative damage.
URI: http://hdl.handle.net/10397/60865
ISSN: 0270-3211 (print)
1520-6866 (online)
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