Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/60680
Title: Enantioselective, copper(I) -catalyzed three-component reaction for the synthesis of beta,gamma-alkynyl alpha-amino acid derivatives
Authors: Shao, ZH
Pu, XW
Li, XJ
Fan, BM
Chan, ASC
Issue Date: 2009
Publisher: Pergamon Press
Source: Tetrahedron : asymmetry, 2009, v. 20, no. 2, p. 225-229 How to cite?
Journal: Tetrahedron : asymmetry 
Abstract: The first catalytic asymmetric three-component reaction of ethyl glyoxylate, para-anisidine, and aliphatic, aromatic alkynes catalyzed by CuOTf 0.5C(6)H(6)/pybox 7 has been developed. The protocol provided the corresponding chiral beta,delta-alkynyl alpha-amino acid derivatives in good yields and 66-74% ee.
URI: http://hdl.handle.net/10397/60680
ISSN: 0957-4166
EISSN: 1362-511X
DOI: 10.1016/j.tetasy.2009.01.006
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