The new advances in sulforaphen

Abstract

萝卜硫素 (1 异硫氰酸 4 甲磺酰基丁烷 )是蔬菜中所发现的抗癌效果最好的植物活性物质 ,能够刺激人或动物细胞产生仅对身体有益的Ⅱ型酶 ,同时抑制Ⅰ型酶的产生 ,使细胞形成对抗外来致癌物浸蚀的膜 ,达到抗癌效果。本文主要对萝卜硫素的抗癌机制、生理功能、生产方法做了详细说明 Sulforaphen[1 isothiocyanato 4 (methysulfiny) butane]can be obtained in cruciferous vegetables as one of the products of enzymatic or acid hydrolysis of glucoraphanin,which has been indentificafied the best anticarcinogenic activity.The chemprotective effect of sulforaphen is thought to be related to its ability as a monofunctional inducer which can induce the production of beneficial 2穑瑁幔螅? Ⅱ enzyme to human organimism selectively without the induction of phase Ⅰ enzyme,and the former can urge cells to form the membrance to act against those external chemical carcinogenesis.In this paper,a review was presented on the anticarcinogenic mechanisms,physiological function and the methods in detail as well as the isolation and purification roughly.