Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/55446
Title: Preparation of different sized nano-silver loaded on functionalized graphene oxide with highly effective antibacterial properties
Authors: Chen, X
Huang, X
Zheng, C
Liu, Y
Xu, T
Liu, J
Issue Date: 2015
Publisher: Royal Society of Chemistry
Source: Journal of materials chemistry B, 2015, v. 3, no. 35, p. 7020-7029 How to cite?
Journal: Journal of materials chemistry B 
Abstract: Graphene oxide (GO) has attracted great interest in many different areas, as a delivery vehicle for antibacterial agents, and has shown high potential. Although silver nanoparticles (AgNPs) have a strong antibacterial effect, the biological application of AgNPs is often hindered by their aggregation and low stability. In this study, we developed an approach of polyoxyethylene bis(amine) (PEG) directed AgNPs grown on GO, then we combined the two materials to prepare a series of functionalized GO bearing different sized AgNPs, and studied the size effects of AgNPs on growth inhibition of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). We evaluated the antibacterial effect of GO@PEG@AgNPs on E. coli and S. aureus by various methods such as minimum inhibitory concentration (MIC) experiment, cell wall/membrane integrity assay and scanning electron microscopy (SEM) characterisation of bacterial morphology. The GO@PEG@AgNPs composites exhibited markedly higher antibacterial efficacy than AgNPs alone. The smallest GO@PEG@AgNPs (10 nm) particularly demonstrated higher antibacterial activity than other sizes (30, 50, and 80 nm). We believe that these findings contribute to great potential application as a regulated graphene-based antibacterial solution.
URI: http://hdl.handle.net/10397/55446
ISSN: 2050-750X
EISSN: 2050-7518
DOI: 10.1039/c5tb00280j
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

35
Last Week
0
Last month
Citations as of Jan 22, 2019

WEB OF SCIENCETM
Citations

33
Last Week
1
Last month
Citations as of Jan 24, 2019

Page view(s)

88
Last Week
0
Last month
Citations as of Jan 13, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.