Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/44091
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dc.contributorDepartment of Health Technology and Informaticsen_US
dc.creatorLam, Jen_US
dc.creatorYing, Men_US
dc.creatorCheung, SYen_US
dc.creatorYeung, KHen_US
dc.creatorYu, PHen_US
dc.creatorCheng, HCen_US
dc.creatorAhuja, ATen_US
dc.date.accessioned2016-06-07T06:37:56Z-
dc.date.available2016-06-07T06:37:56Z-
dc.identifier.issn0172-4614en_US
dc.identifier.urihttp://hdl.handle.net/10397/44091-
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlagen_US
dc.rights© Georg Thieme Verlag KG Stuttgart · New Yorken_US
dc.rightsThis is the accepted version of the work. The final published article is available at https://doi.org/10.1055/s-0034-1384939.en_US
dc.subjectHead/necken_US
dc.subjectLymph nodesen_US
dc.subjectMetastasesen_US
dc.subjectUltrasound-power doppleren_US
dc.titleA comparison of the diagnostic accuracy and reliability of subjective grading and computer-aided assessment of intranodal vascularity in differentiating metastatic and reactive cervical lymphadenopathyen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage63en_US
dc.identifier.epage67en_US
dc.identifier.volume37en_US
dc.identifier.issue1en_US
dc.identifier.doi10.1055/s-0034-1384939en_US
dcterms.abstractPurpose: Ultrasound is a well-established imaging modality in the assessment of malignant cervical lymphadenopathy. With the use of Doppler ultrasound, intranodal vascularity can be evaluated. However, the major limitation of ultrasound is operator dependency. Therefore, this study aimed to evaluate and compare the diagnostic accuracy and reliability of the subjective grading and computer-aided approach in assessing intranodal vascularity for the differentiation of benign and malignant lymph nodes.en_US
dcterms.abstractMaterials and Methods: The present study retrospectively assessed 99 power Doppler ultrasound images of cervical lymph nodes and evaluated the degree of intranodal vascularity using qualitative subjective grading (QSG) and quantitative computer-aided (QCA) methods. The diagnostic accuracy of the two methods in distinguishing metastatic and reactive nodes and their inter- and intra-rater reliability in assessing intranodal vascularity were evaluated and compared.en_US
dcterms.abstractResults: The results showed that the QCA method was more accurate than the QSG method with a significantly higher sensitivity (67.8 % and 61.9 %, respectively, p < 0.05) and specificity (73.3 % and 57.3 %, respectively, p < 0.05). Using the intranodal vascularity index as determined by the QCA approach, the optimum cut-off to differentiate metastatic and reactive cervical lymph nodes was 32 %. The QCA method showed higher inter- and intra-rater reliability than the QSG method.en_US
dcterms.abstractConclusion: In the assessment of the degree of intranodal vascularity, the QCA method was more accurate and reliable than the QSG method in distinguishing metastatic and reactive lymph nodes.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationUltraschall in der Medizin, Feb. 2016, v. 37, no. 1, p. 63-67en_US
dcterms.isPartOfUltraschall in der Medizinen_US
dcterms.issued2016-02-
dc.identifier.isiWOS:000370626700007-
dc.identifier.scopus2-s2.0-84958169007-
dc.identifier.rosgroupid2015001918-
dc.description.ros2015-2016 > Academic research: refereed > Publication in refereed journalen_US
dc.description.oaAccepted Manuscripten_US
dc.identifier.FolderNumberHTI-0155-
dc.description.fundingSourceSelf-fundeden_US
dc.description.pubStatusPublisheden_US
dc.identifier.OPUS6616779-
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