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Title: Randomized clinical trial of myopia control in myopic schoolchildren using the defocus incorporated soft contact (DISC) lens
Authors: Lam, CSY 
Tang, WC
Tang, YY
Tse, DY
To, CH 
Issue Date: 2010
Source: IMC 2010 13th International Myopia Conference 2010, July 26-29, 2010, Tubingen, Germany How to cite?
Abstract: Purpose: To determine whether wearing of a special designed ‘Defocus Incorporated Soft Contact’ (DISC) lens reduced the progression of myopia in Hong Kong schoolchildren over 2 years.
Methods: Two hundred and twenty one healthy myopic (-1D to -5D with astigmatism less than 1D) Hong Kong Chinese schoolchildren aged between 8 to 13 years were recruited. They had no prior use of bifocal or progressive lenses and no contact lens experience. The subjects were randomly allocated to wear either the DISC contact lenses (treatment group) or the single vision (SV) contact lenses (control group). Their refractive error and related ocular parameters (e.g. axial length) were measured every 6 months for 2 years. Both the subjects and the optometrist who performed eye data measurement were masked. Cycloplegic objective refraction and axial length were measured by using Shin-Nippon NVision-K 5001 autorefractor and IOL Master respectively. The changes in spherical equivalent refractive error and axial length between two groups in 2 years were compared by using unpaired t-test.
Results: So far 65 subjects had worn contact lenses for 2 years and completed the study. In total there are 141 subjects still enroled in the project, and 80 subjects quitted the study. After 2-year contact lens wear, data from the right eyes showed that the control group (n= 32) had more myopia progression (mean differences: -0.35D) than the treatment group (n= 33) (p < 0.01). Axial length data was consistent with the refractive findings, the children wearing SV lenses showed significantly more axial elongation in their eyes than those wearing the DISC lenses (mean difference = 0.16mm, p < 0.01).
Discussion and Conclusions: The DISC lens showed significant effect on retarding myopia progression in schoolchildren according statistics.
Appears in Collections:Conference Paper

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