Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/36364
Title: Potential therapeutic effects of Baicalein, Baicalin, and Wogonin in ocular disorders
Authors: Xiao, JR
Do, CW 
To, CH 
Issue Date: 2014
Publisher: Mary Ann Liebert Inc.
Source: Journal of ocular pharmacology and therapeutics, 2014, v. 30, no. 8, p. 605-614 How to cite?
Journal: Journal of ocular pharmacology and therapeutics 
Abstract: Ocular diseases such as cataract, glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy are the leading causes of blindness. The elderly population is at particular risk of developing one or more of these age-related ocular diseases. By virtue of multiple bioactivities, effort has been made to develop dietary flavonoids as complimentary therapies for ocular disorders. Dietary intake of flavonoids has been reported to reduce the risk of cataract and AMD. This review focuses on the main flavones baicalein, baicalin, and wogonin isolated from the Chinese medicinal herb, Scutellariae radix (SR), which has been widely used in Asian countries for the treatment of many diseases. Interest in SR has grown recently following new findings that suggest multiple routes of therapeutic action. This review will summarize the diverse pharmacological properties, therapeutic roles, and mechanisms of these flavones of SR in cellular and animal models of ocular diseases.
URI: http://hdl.handle.net/10397/36364
ISSN: 1080-7683 (print)
1557-7732 (online)
DOI: 10.1089/jop.2014.0074
Appears in Collections:Journal/Magazine Article

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