Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/36235
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dc.contributorSchool of Nursing-
dc.contributorDepartment of Applied Mathematics-
dc.creatorYang, L-
dc.creatorChan, KH-
dc.creatorSuen, LKP-
dc.creatorChan, KP-
dc.creatorWang, XL-
dc.creatorCao, PH-
dc.creatorHe, DH-
dc.creatorPeiris, JSM-
dc.creatorWong, CM-
dc.date.accessioned2016-04-15T08:36:53Z-
dc.date.available2016-04-15T08:36:53Z-
dc.identifier.urihttp://hdl.handle.net/10397/36235-
dc.language.isoenen_US
dc.publisherPublic Library of Scienceen_US
dc.rights© 2015 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rightsThe following publication: Yang L, Chan KH, Suen LKP, Chan KP, Wang X, Cao P, et al. (2015) Impact of the 2009 H1N1 Pandemic on Age-Specific Epidemic Curves of Other Respiratory Viruses: A Comparison of Pre-Pandemic, Pandemic and Post-Pandemic Periods in a Subtropical City. PLoS ONE 10(4): e0125447 is available at https://doi.org/10.1371/journal.pone.0125447en_US
dc.titleImpact of the 2009 H1N1 pandemic on age-specific epidemic curves of other respiratory viruses : a comparison of pre-pandemic, pandemic and post-pandemic periods in a subtropical cityen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.volume10en_US
dc.identifier.issue4en_US
dc.identifier.doi10.1371/journal.pone.0125447en_US
dcterms.abstractBackground: The 2009 H1N1 influenza pandemic caused offseason peaks in temperate regions but coincided with the summer epidemic of seasonal influenza and other common respiratory viruses in subtropical Hong Kong. This study was aimed to investigate the impact of the pandemic on age-specific epidemic curves of other respiratory viruses.-
dcterms.abstractMethods: Weekly laboratory-confirmed cases of influenza A (subtypes seasonal A(H1N1), A(H3N2), pandemic virus A(H1N1) pdm09), influenza B, respiratory syncytial virus (RSV), adenovirus and parainfluenza were obtained from 2004 to 2013. Age-specific epidemic curves of viruses other than A(H1N1) pdm09 were compared between the pre-pandemic (May 2004 - April 2009), pandemic (May 2009 - April 2010) and post-pandemic periods (May 2010 - April 2013).-
dcterms.abstractResults: There were two peaks of A(H1N1) pdm09 in Hong Kong, the first in September 2009 and the second in February 2011. The infection rate was found highest in young children in both waves, but markedly fewer cases in school children were recorded in the second wave than in the first wave. Positive proportions of viruses other than A(H1N1) pdm09 markedly decreased in all age groups during the first pandemic wave. After the first wave of the pandemic, the positive proportion of A(H3N2) increased, but those of B and RSV remained slightly lower than their pre-pandemic proportions. Changes in seasonal pattern and epidemic peak time were also observed, but inconsistent across virus-age groups.-
dcterms.abstractConclusion: Our findings provide some evidence that age distribution, seasonal pattern and peak time of other respiratory viruses have changed since the pandemic. These changes could be the result of immune interference and changing health seeking behavior, but the mechanism behind still needs further investigations.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationPLoS one, 2015, v. 10, no. 4, e0125447-
dcterms.isPartOfPLoS one-
dcterms.issued2015-
dc.identifier.isiWOS:000353713100092-
dc.identifier.pmid25928217-
dc.identifier.eissn1932-6203en_US
dc.identifier.rosgroupid2014000274-
dc.description.ros2014-2015 > Academic research: refereed > Publication in refereed journalen_US
dc.description.validate201811_a bcmaen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_IR/PIRAen_US
dc.description.pubStatusPublisheden_US
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