Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/35853
Title: Phase-Transfer-Catalyst-Mediated domino reaction of gamma-Nitro Ketones with Chalcones : approach to functionalized Six-Membered-Ring Carbocycles
Authors: Yu, L
Yang, QJ
Li, PF
Keywords: Synthetic methods
Phase-transfer catalysis
Cyclization
Domino reactions
Aldol reactions
Michael addition
Enones
Issue Date: 2014
Publisher: Wiley-VCH
Source: European journal of organic chemistry, 2014, no. 33, p. 7499-7504 How to cite?
Journal: European journal of organic chemistry 
Abstract: Domino reactions between -nitro ketones and chalcones for the construction of functionalized six-membered-ring carbocycles using a phase-transfer catalyst have been developed. In the presence of tetrabutylammonium iodide and potassium hydroxide, domino reactions between -nitro ketones and a series of chalcones proceeded smoothly to give the cyclic products in moderate to high yields with high diastereoselectivities. Importantly, multiply substituted and functionalized six-membered-ring carbocycles could be efficiently prepared in one pot using this domino strategy.
URI: http://hdl.handle.net/10397/35853
ISSN: 1434-193X (print)
1099-0690 (online)
DOI: 10.1002/ejoc.201403075
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