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Title: Antitumor effect between anti-tumor drug and antimicrobial peptides loaded in the nanofibrous membrane
Authors: Zhang, J
Li, Y 
Li, JS
Liu, X
Li, Z
Keywords: Nanofibers
Issue Date: 2014
Publisher: Textile Bioengineering & Informatics Society Ltd
Source: Textile bioengineering and informatics symposium proceedings, 2014, vols 1 and 2, 2014, p. 252-258 How to cite?
Abstract: Present study introduced a novel anti-tumor membrane based on Poly (L-lactic acid) (PLLA) and keratin precipitates from wool hydrolyzed solution by electrospinning technology. Both the anti-tumor drug and antimicrobial attacin-2 was introduced into this anti-tumor nanofibrous drug delivery system. The antitumor effect between anti-tumor drug and attacin-2. were investigated. The anti-tumor effect test indicated that after adding antimicrobial peptides, the growth rate of tumor cells has been dramatically decreased after 72 hour cultivation. The biological antimicrobial peptides have a long and sustained inhibition on tumor cells which compensates the short effect of chemical antitumor drugs. The experiments demonstrated that the antitumor effect between chemical antitumor drug and antimicrobial peptides could inhibit the proliferation of tumor cells.
Description: 7th Textile Bioengineering and Informatics Symposium (TBIS 2014) / 5th Asian Protective Clothing Conference (APCC 2014), Hong Kong, Peoples R China, 6-8 August 2014
ISSN: 1942-3438
Appears in Collections:Conference Paper

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