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Title: Case report : postradiation chondrosarcoma with a short latency period of 6 months
Authors: Yang, S
Tang, W
Tang, XF
Xuan, M
Guo, LJ
Wang, XY
Loo, WTY
Liu, Q
Chow, LWC
Cheung, MNB
Tsang, W 
Keywords: Basal cell carcinoma
Computed tomography
Maxillofacial chondrosarcoma
Postradiation chondrosarcoma
Issue Date: 2014
Publisher: Wichtig Editore
Source: International journal of biological markers, 2014, v. 29, no. 4, p. e440-e444 How to cite?
Journal: International journal of biological markers 
Abstract: We describe a case of postradiation chondrosarcoma after basal cell carcinoma treatment. At the time he presented, the patient was a 35-year-old man who had received radiotherapy at a dose of 70 Gy for 8 weeks. Six months after radiation treatment, a rapidly growing mass at the upper right alveolar ridge of the gums, where radiation had been given, was diagnosed as chondrosarcoma. Generally, chondrosarcoma occurs after a latency period of several years following radiation. However, there are a few relevant reports indicating that maxillofacial chondrosarcoma can develop after radiotherapy for basal cell carcinoma, with a short latency of 6 months. We hypothesize that the dosage and treatment time of radiation may have played a role in the opening/closing of the Hh-signaling pathway in the case of this patient.
ISSN: 0393-6155
DOI: 10.5301/jbm.5000109
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