Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/33942
Title: Direct aldol and tandem Mannich reactions in room temperature ammonia solutions
Authors: Feng, L
Xu, L
Lam, K
Zhou, Z
Yip, CW
Chan, ASC
Keywords: Aldol reaction
Ammonia solutions
Mannich reaction
Tandem
Issue Date: 2005
Publisher: Pergamon Press
Source: Tetrahedron letters, 2005, v. 46, no. 50, p. 8685-8689 How to cite?
Journal: Tetrahedron letters 
Abstract: An economical, simple, and efficient direct aldol reaction via the double activation of both aldehydes and ketones by ammonia has been developed. An unprecedented tandem Mannich reaction was observed when hydroxybenzaldehydes, pyrrole-2-carboxyaldehyde, and indole-3-carboxyaldehyde were employed to afford 2,2-dimethyl-6-aryl-4-pyrilidinones in moderate to good yields.
URI: http://hdl.handle.net/10397/33942
ISSN: 0040-4039
EISSN: 1873-3581
DOI: 10.1016/j.tetlet.2005.10.050
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