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http://hdl.handle.net/10397/32916| Title: | Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry | Authors: | Zhang, L Yu, H Li, WM Cheung, MC Pang, YP Lin, G Wang, YT Zuo, Z Han, YF |
Keywords: | Alzheimer's disease Bis(7)-tacrine LC-MS-MS Rat plasma |
Issue Date: | 2008 | Publisher: | John Wiley & Sons | Source: | Biomedical chromatography, 2008, v. 22, no. 4, p. 414-420 How to cite? | Journal: | Biomedical chromatography | Abstract: | The current study aims to develop a specific and sensitive LC-MS/MS method for determination of bis(7)-tacrine (B7T) in rat plasma. A 100 ?gL plasma sample was extracted with ethyl acetate. B7T and the internal standard (IS), pimozide, in the samples were then analyzed with LC-MS/MS in positive electrospray ioni | URI: | http://hdl.handle.net/10397/32916 | ISSN: | 0269-3879 | EISSN: | 1099-0801 | DOI: | 10.1002/bmc.949 |
| Appears in Collections: | Journal/Magazine Article |
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