Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/32750
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dc.contributor.authorLin, Zen_US
dc.contributor.authorChen, Len_US
dc.contributor.authorFang, Yen_US
dc.contributor.authorCai, Aen_US
dc.contributor.authorZhang, Ten_US
dc.contributor.authorWu, VWCen_US
dc.date.accessioned2015-07-14T01:33:06Z-
dc.date.available2015-07-14T01:33:06Z-
dc.date.issued2013-
dc.identifier.issn1043-3074-
dc.identifier.urihttp://hdl.handle.net/10397/32750-
dc.description.abstractBackground: The purpose of this study was to evaluate the correlations of thyroid antibody and thyroid hormone in postradiotherapy (post-RT) patients with nasopharyngeal carcinoma (NPC). Methods: Serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroperoxidase antibody (anti-TPO), and thyroglobulin antibody (anti-TG) levels of 55 patients with NPC were taken before RT and at 3, 6, 12, and 18 months after RT. Patients with hypothyroidism at 18 months after RT and those with normal thyroid function were categorized into the hypo and normal groups, respectively. The thyroid antibody levels were compared between the 2 groups, and the correlations of thyroid antibody and thyroid hormone were evaluated for the hypo group. Results: The anti-TPO and anti-TG of the hypo group were higher than the normal group. In the hypo group, there was a positive correlation (r = 0.51) between TSH and anti-TG and a negative correlation between fT4 and anti-TPO (r = -0.55). Conclusion: There were correlations of the thyroid antibody and thyroid hormone levels in patients with radiation-induced hypothyroidism.en_US
dc.description.sponsorshipDepartment of Health Technology and Informaticsen_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofHead and Necken_US
dc.subjectNasopharyngeal carcinomaen_US
dc.subjectPostradiotherapyen_US
dc.subjectRadiation-induced hypothyroidismen_US
dc.subjectThyroid antibodiesen_US
dc.subjectThyroid hormonesen_US
dc.titleLongitudinal study on the correlations of thyroid antibody and thyroid hormone levels after radiotherapy in patients with nasopharyngeal carcinoma with radiation-induced hypothyroidismen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.doi10.1002/hed.23285-
dc.identifier.isiWOS:000329502800006-
dc.identifier.scopus2-s2.0-84875689271-
dc.identifier.rosgroupidr71721-
dc.description.ros2013-2014 > Academic research: refereed > Publication in refereed journal-
Appears in Collections:Journal/Magazine Article
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