Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/32274
Title: A new method for computing the uniaxial modulus of articular cartilages using modified inhomogeneous triphasic model
Authors: Niu, H
Wang, Q
Zheng, Y 
Fan, Y
Keywords: Articular cartilage
Inhomogeneous
Osmotic pressure
Triphasic model
Unaxial module
Issue Date: 2010
Publisher: Springer Heidelberg
Source: Acta Mechanica Sinica/Lixue Xuebao, 2010, v. 26, no. 1, p. 121-126 How to cite?
Journal: Acta Mechanica Sinica/Lixue Xuebao 
Abstract: It is well known that subtle changes in structure and tissue composition of articular cartilage can lead to its degeneration. The present paper puts forward a modified layered inhomogeneous triphasic model with four parameters based on the inhomogeneous triphasic model proposed by Narmoneva et al. Incorporating a piecewise fitting optimization criterion, the new model was used to obtain the uniaxial modulus Ha, and predict swelling pattern for the articular cartilage based on ultrasound-measured swelling strain data. The results show that the new method can be used to provide more accurate estimation on the uniaxial modulus than the inhomogeneous triphasic model with three parameters and the homogeneous mode, and predict effectively the swelling strains of highly nonuniform distribution of degenerated articular cartilages. This study can provide supplementary information for exploring mechanical and material properties of the cartilage, and thus be helpful for the diagnosis of osteoarthritis-related diseases.
URI: http://hdl.handle.net/10397/32274
DOI: 10.1007/s10409-009-0287-x
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