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Title: Evaluation of the accuracy of volume determination on the orbit and eyeball using MRI
Authors: Chau, A
Fung, K 
Yap, M 
Keywords: Diagnostic radiology physics
Image analysis
Image handling
Image processing
Issue Date: 2005
Publisher: W.B. Saunders
Source: Radiography, 2005, v. 11, no. 1, p. 35-39 How to cite?
Journal: Radiography 
Abstract: This study reports a calibration carried out on phantoms simulating the orbit and eyeball to evaluate the accuracy of volumetric determination using MRI DICOM (Digital Imaging and Communication in Medicine) images. Ten tailor-made spherical silicon balls ranging in size from 5 to 14 cm3 and 10 silicon moulds of orbits from 10 human dried skulls were used to simulate the eyes and orbits, respectively. The CISS (Constructive interference in steady state, TR/TE = 16/8 ms) T2-weighted sequence was taken using a Siemens MRI scanner. The volume of each phantom was computed and compared with the known physical volumes. The computed and physical volumes were highly correlated for both eyeball (r = 0.997) and the orbit (r = 0.992) phantoms. Coefficients of variation of the computed and physical volumes were low. Consequently, it is possible to apply a calibration value to the computed volume to derive the physical volume with a high level of confidence. We conclude that with appropriate calibration, it is viable to use MRI DICOM images to derive the volume of the eyeball and the orbit.
ISSN: 1078-8174
DOI: 10.1016/j.radi.2004.10.004
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