Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/31433
Title: Novel nanofibrous scaffold to improve wound healing
Authors: Mak, EYW
Leung, WWF 
Issue Date: 2013
Publisher: American Society of Mechanical Engineers (ASME)
Source: ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), 2013, v. 3 B How to cite?
Abstract: An antibacterial and biocompatible scaffold for fibroblasts proliferation based on chitosan has been developed. Chitosan solution is electrospun into uniform fibers of 100-200 nm in diameter that mimic the extracellular matrix of human skin. The fibrous mats are successfully cross-linked to be stable in acidic solution, which can be used to treat acute wounds. The crosslinked fibrous mats display antibacterial properties toward Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The mechanical properties of fibrous mats are shown to be comparable to native skin dermis which protects the skin wound.
Description: ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013, San Diego, CA, 15-21 November 2013
URI: http://hdl.handle.net/10397/31433
ISBN: 9780791856222
DOI: 10.1115/IMECE2013-64223
Appears in Collections:Conference Paper

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