Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/30862
Title: Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems
Authors: Chan, SH
Lam, KH
Li, YM
Xu, L
Tang, W
Lam, FL
Lo, WH 
Yu, WY 
Fan, Q
Chan, ASC
Issue Date: 2007
Publisher: Pergamon Press
Source: Tetrahedron : asymmetry, 2007, v. 18, no. 22, p. 2625-2631 How to cite?
Journal: Tetrahedron : asymmetry 
Abstract: The iridium complex-catalyzed asymmetric hydrogenation of quinolines in a DMPEG/hexane biphasic system was studied. Catalysts with C-2-symmetric ligands such as Xyl-P-Phos, Cl-MeO-BIPHEP, SYNPHOS, and DiluorPhos are highly effective for this type of reaction. Most of the catalysts tested can be retained in DMPEG (M-n = 500), and the asymmetric hydrogenation of various quinoline substrates can be carried out in DMPEG/hexane biphasic system with up to 92% ee. The catalysts and the products can be separated via simple phase separation, and the reactivity/stereoselectivity of the catalysts can be retained for at least three reaction cycles.
URI: http://hdl.handle.net/10397/30862
ISSN: 0957-4166
EISSN: 1362-511X
DOI: 10.1016/j.tetasy.2007.10.034
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

41
Last Week
0
Last month
Citations as of Feb 26, 2017

WEB OF SCIENCETM
Citations

39
Last Week
1
Last month
0
Citations as of Aug 21, 2017

Page view(s)

58
Last Week
1
Last month
Checked on Aug 21, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.