Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/30543
Title: Stereoselective synthesis of the C1-C12 fragment of the thuggacins
Authors: Tang, S
Xu, Z
Ye, T 
Issue Date: 2009
Publisher: Pergamon Press
Source: Tetrahedron : asymmetry, 2009, v. 20, no. 17, p. 2027-2032 How to cite?
Journal: Tetrahedron : asymmetry 
Abstract: A concise asymmetric synthesis of the C1-C12 fragment of the antibacterial natural product thuggacins has been achieved. The stereochemistry of this fragment was established efficiently via stereoselective reduction and Evans-aldol condensation. Hanztsch's method and a Horner-Wadsworth-Emmnons reaction were employed for thiazole formation and the construction of the E-α,β-unsaturated double bond.
URI: http://hdl.handle.net/10397/30543
ISSN: 0957-4166
EISSN: 1362-511X
DOI: 10.1016/j.tetasy.2009.08.015
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