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Title: The application of organic electrochemical transistors in biosensors
Authors: Yan, F 
Lin, P
Chan, HLW 
Issue Date: 2010
Publisher: Electrochemical Society
Source: ECS transactions, 2010, v. 33, no. 5, p. 399-408 How to cite?
Journal: ECS transactions 
Abstract: Ion-sensitive properties of organic electrochemical transistors (OECT) based on Poly(3,4-ethylenedioxythiophene): poly(styrene sulfonic acid) (PEDOT:PSS) are systematically studied for the first time. The transfer curve (IDS ∼ VG) of an OECT shifts to lower gate voltage horizontally with the increase of the concentration of cations, including H +, K+, Na+, Ca2+, and Al 3+, in the electrolyte. Nernstian relationships between the shift of the gate voltage and the concentrations of the cations have been obtained. Cell-based biosensors with cancer cells cultivated on top of the OECTs have been studied. The activities of the cells under the effect of trypsin have been monitored by characterizing the OECTs. It has been found that the performance of the device is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the adherent cells and the active layer of the OECT.
Description: 10th Symposium on Thin Film Transistor Technologies, TFT 10 - 218th ECS Meeting, Las Vegas, NV, 11-15 October 2010
ISBN: 9781566778244
ISSN: 1938-5862
EISSN: 1938-6737
DOI: 10.1149/1.3481263
Appears in Collections:Conference Paper

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