Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/27360
Title: Clinical device-related article evaluation of morphology and functions of a foldable capsular vitreous body in the rabbit eye
Authors: Chen, J
Gao, Q
Liu, Y
Ge, J
Cao, X
Luo, Y
Huang, D
Zhou, G
Lin, S
Lin, J
To, CH 
Siu, AW
Issue Date: 2011
Source: Journal of biomedical materials research. Part B, Applied biomaterials, 2011, v. 97 b, no. 2, p. 396-404
Abstract: We previously proposed a new strategy to replace a vitreous body with a novel foldable capsular vitreous body (FCVB). In this study, the FCVB was designed to mimic natural vitreous morphology, and evaluate its physiological functions compared with traditional silicone oil substitutes, in an established rabbit model of proliferative vitreoretinopathy. We found that FCVB was a very good replacement for closely mimicking the morphology and restoring the physiological functions, such as the support, refraction, and cellular barriers, of the rabbit vitreous body. The study has provided us with a novel research and therapy strategy that could effectively mimic the morphology and physiological function of the rabbit vitreous body.
Keywords: device
PVR
rabbit
vitreous substitute
Publisher: John Wiley & Sons
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 
ISSN: 1552-4973
EISSN: 1552-4981
DOI: 10.1002/jbm.b.31812
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