Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/27289
Title: Effect of 4 weeks of Acu-TENS on functional capacity and β-endorphin level in subjects with chronic obstructive pulmonary disease : a randomized controlled trial
Authors: Ngai, SPC
Jones, AYM
Hui-Chan, CWY
Ko, FWS
Hui, DSC
Keywords: β-Endorphin
Acu-TENS
COPD
Cumulative effect
Issue Date: 2010
Publisher: Elsevier Science Bv
Source: Respiratory physiology and neurobiology, 2010, v. 173, no. 1, p. 29-36 How to cite?
Journal: Respiratory Physiology and Neurobiology 
Abstract: Our recent studies showed that one session of transcutaneous electrical nerve stimulation on acupoints (Acu-TENS) improved forced expiratory volume in 1s (FEV1) in patients with chronic obstructive pulmonary disease (COPD). This study investigated the effect of 4-week Acu-TENS on physical and psychosocial function in these patients. Twenty-eight patients were randomly allocated to receive 4-weeks of 45-min, 5-days/week, of either Acu-TENS (over Dingchuan), Placebo-TENS (same protocol without electrical output), or Sham-TENS (over the patellae). Variables measured before and after intervention included FEV1, forced vital capacity (FVC), 6-min walk distance (6MWD), St. George's Respiratory Questionnaire score (SGRQ), β-endorphin and blood inflammatory marker levels. Only the Acu-TENS group attained significant improvement in FEV1 (p=0.046), physical activity (p=0.007) and total SGRQ score (p=0.028). The increase in β-endorphin (p=0.012) correlated positively with the improvement in FEV1 (r=0.526, p=0.008). To conclude, 4 weeks of Acu-TENS improved the functional capacity of patients with COPD, probably due to the bronchodilation induced by β-endorphin elevation.
URI: http://hdl.handle.net/10397/27289
DOI: 10.1016/j.resp.2010.06.005
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