Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/26858
Title: On ultrasound waves guided by bones with coupled soft tissues : a mechanism study and in vitro calibration
Authors: Chen, J
Su, Z 
Keywords: Bone assessment
Coupling effect
Quantitative ultrasound (QUS)
Soft tissue
Ultrasound waves
Issue Date: 2014
Publisher: Elsevier
Source: Ultrasonics, 2014, v. 54, no. 5, p. 1186-1196 How to cite?
Journal: Ultrasonics 
Abstract: The influence of soft tissues coupled with cortical bones on precision of quantitative ultrasound (QUS) has been an issue in the clinical bone assessment in conjunction with the use of ultrasound. In this study, the effect arising from soft tissues on propagation characteristics of guided ultrasound waves in bones was investigated using tubular Sawbones phantoms covered with a layer of mimicked soft tissue of different thicknesses and elastic moduli, and an in vitro porcine femur in terms of the axial transmission measurement. Results revealed that presence of soft tissues can exert significant influence on the propagation of ultrasound waves in bones, leading to reduced propagation velocities and attenuated wave magnitudes compared with the counterparts in a free bone in the absence of soft tissues. However such an effect is not phenomenally dependent on the variations in thickness and elastic modulus of the coupled soft tissues, making it possible to compensate for the coupling effect regardless of the difference in properties of the soft tissues. Based on an in vitro calibration, this study proposed quantitative compensation for the effect of soft tissues on ultrasound waves in bones, facilitating development of high-precision QUS.
URI: http://hdl.handle.net/10397/26858
ISSN: 0041-624X
EISSN: 1874-9968
DOI: 10.1016/j.ultras.2013.08.002
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