Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/26801
Title: Characterization and antibacterial activity of silver nanoparticles prepared with a fungal exopolysaccharide in water
Authors: Chen, X
Yan, JK
Wu, JY 
Keywords: Antibacterial activity
Exopolysaccharide
Medicinal fungus
Silver nanoparticles
Issue Date: 2015
Publisher: Elsevier
Source: Food hydrocolloids, 2015 How to cite?
Journal: Food Hydrocolloids 
Abstract: This work demonstrates a simple and feasible approach for the synthesis of silver nanoparticles (AgNPs) in water with a high molecular weight (MW) exopolysaccharide fraction, EPS1 produced by a medicinal fungus Cs-HK1. The formation and properties of AgNPs were evaluated at various temperatures, time periods, and silver nitrate/EPS1 concentrations in water. At suitable conditions (100°C, 60min and 10mM AgNO3 with 1.0mg/mL EPS1), AgNPs were formed with an average diameter of 50nm and a narrow size distribution, remaining as a stable dispersion for at least 2 months. EPS1 may be acting as a reducing and stabilizing agent for the formation of AgNPs, which were attached to the hydroxyl groups of EPS1. The AgNPs formed in EPS1 solution exhibited a concentration-dependent inhibition of both Gram-negative and -positive bacteria but a very low cytotoxicity on the RAW264.7 murine macrophage cells. The results demonstrated the feasibility for green synthesis of AgNPs as potential antibacterial agents using natural polysaccharides dissolved in water.
URI: http://hdl.handle.net/10397/26801
ISSN: 0268-005X
DOI: 10.1016/j.foodhyd.2014.12.032
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