Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/26446
Title: Repeatability of a novel corneal indentation device for corneal biomechanical measurement
Authors: Lam, AKC 
Hon, Y
Leung, LKK
Lam, DCC
Keywords: Corneal biomechanics
Elastic modulus
Intraocular pressure
Stiffness
Issue Date: 2015
Publisher: Wiley-Blackwell
Source: Ophthalmic and physiological optics, 2015, v. 35, no. 4, p. 455-461 How to cite?
Journal: Ophthalmic and physiological optics 
Abstract: Purpose: The aim of the study was to evaluate the repeatability of a new device for measuring corneal biomechanics. Methods: Twenty-nine normal subjects aged 20-28 years (23.4 ± 1.7 years) underwent measurements of corneal stiffness and tangent elastic modulus using a novel corneal indentation device. Corneal topography, axial biometry and Goldmann applanation tonometry were also performed during the visit. Subjects returned after about 1 week, at approximately the same time, and with the corneal biomechanics, corneal topography and Goldmann applanation tonometry measured again. Both the intrasession and intersession repeatability was assessed. Results: Both the corneal stiffness and tangent elastic modulus demonstrated good intrasession repeatability (corneal stiffness: coefficient of variation = 7.32%, intraclass correlation coefficient = 0.75; tangent elastic modulus: coefficient of variation = 7.34%, intraclass correlation coefficient = 0.84). The mean modulus after normalised to normal intraocular pressure of 15.5 mmHg was 0.755 ± 0.159 MPa. There was no significant difference between the two visits (paired t-tests: p > 0.05). The repeatability [1.96 times the standard deviation (S.D.) of the intersession difference] of the corneal stiffness and the tangent elastic modulus was 0.0022 N mm-1 and 0.197 MPa, respectively. Conclusion: The corneal indentation device has good intrasession and intersession repeatability. It has good potential to measure corneal biomechanics clinically, even at different corneal regions.
URI: http://hdl.handle.net/10397/26446
ISSN: 0275-5408
EISSN: 1475-1313
DOI: 10.1111/opo.12219
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

5
Last Week
0
Last month
0
Citations as of Sep 11, 2017

WEB OF SCIENCETM
Citations

5
Last Week
0
Last month
0
Citations as of Sep 16, 2017

Page view(s)

32
Last Week
1
Last month
Checked on Sep 17, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.