Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/25124
Title: A prospective randomized clinical trial to investigate the effect of silicone gel sheeting (Cica-Care) on post-traumatic hypertrophic scar among the Chinese population
Authors: Li-Tsang, CWP 
Lau, JCM
Choi, J
Chan, CCC
Jianan, L
Keywords: Chinese population
Hypertrophic scar
Pressure therapy
Randomized clinical trial
Issue Date: 2006
Publisher: Elsevier Sci Ltd
Source: Burns, 2006, v. 32, no. 6, p. 678-683 How to cite?
Journal: Burns 
Abstract: Background: This study aimed to determine the efficacy of silicone gel (Cica-Care) on severe post-traumatic hypertophic scars among the Chinese population. Method and materials: A randomized clinical trial (RCT) was conducted on 45 Chinese patients with post-traumatic hypertrophic scars. Twenty-two subjects were placed in the experimental group with silicone gel sheeting (SGS) applied 24 h per day for 6 months while all subjects were taught to massage the scar daily for 15 min serving as the control intervention. Scar assessments were conducted regularly to measure the changes in thickness, pigmentation, vascularity, pliability, itchiness and pain. Results: Two-way repeated ANOVA showed a significant difference between MT group and SGS group on scar thickness. The post hoc comparison analysis showed that the difference was significant at the post-2-month (p = 0.008) and post-6-month (p < 0.001) intervention. The SGS group also showed changes in pigmentation which resembled normal skin but no statistical significance was found. Pain, itchiness and pliability were also improved after intervention. Conclusion: This study indicated that silicone gel sheeting (Cica-Care) was effective to reduce thickness, pain, itchiness and pliability of the severe hypertrophic scar among the Chinese population. The moisturization effect of the tough and hard scar might contribute to the reduction of the skin thickness after 6 month's intervention.
URI: http://hdl.handle.net/10397/25124
ISSN: 0305-4179
DOI: 10.1016/j.burns.2006.01.016
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