Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/25071
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | - |
dc.creator | Wang, X | - |
dc.creator | Lv, C | - |
dc.creator | Feng, J | - |
dc.creator | Tang, L | - |
dc.creator | Wang, Z | - |
dc.creator | Liu, Y | - |
dc.creator | Meng, Y | - |
dc.creator | Ye, T | - |
dc.creator | Xu, Z | - |
dc.date.accessioned | 2015-10-13T08:27:53Z | - |
dc.date.available | 2015-10-13T08:27:53Z | - |
dc.identifier.issn | 1660-3397 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/25071 | - |
dc.language.iso | en | en_US |
dc.publisher | MDPI AG | en_US |
dc.rights | © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). | en_US |
dc.rights | The following publication is available at Wang, X.; Lv, C.; Feng, J.; Tang, L.; Wang, Z.; Liu, Y.; Meng, Y.; Ye, T.; Xu, Z. Studies toward the Total Synthesis of Itralamide B and Biological Evaluation of Its Structural Analogs. Mar. Drugs 2015, 13, 2085-2104://dx.doi.org/10.3390/md13042085 | en_US |
dc.subject | Biological study | en_US |
dc.subject | Cyclodepsipeptide | en_US |
dc.subject | Itralamide B | en_US |
dc.subject | Structural analogs | en_US |
dc.subject | Total synthesis | en_US |
dc.title | Studies toward the total synthesis of itralamide B and biological evaluation of its structural analogs | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 2085 | en_US |
dc.identifier.epage | 2104 | en_US |
dc.identifier.volume | 13 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.doi | 10.3390/md13042085 | en_US |
dcterms.abstract | Itralamides A and B were isolated from the lipophilic extract of Lyngbya majuscula collected from the eastern Caribbean. Itralamide B (1) showed cytotoxic activity towards human embryonic kidney cells (HEK293, IC50 = 6 £gM). Preliminary studies disapproved the proposed stereochemistry of itralamide. In this paper, we will provide a full account of the total synthesis of four stereoisomers of itralamide B and the results derived from biological tests of these structural congeners. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Marine drugs, Apr. 2015, v. 13, no. 4, p. 2085-2104 | - |
dcterms.isPartOf | Marine Drugs | - |
dcterms.issued | 2015 | - |
dc.identifier.scopus | 2-s2.0-84928538616 | - |
dc.identifier.pmid | 25871289 | - |
dc.identifier.rosgroupid | 2014002072 | - |
dc.description.ros | 2014-2015 > Academic research: refereed > Publication in refereed journal | en_US |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
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Wang_Synthesis_Itralamide_B.pdf | 961.37 kB | Adobe PDF | View/Open |
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