Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/25071
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dc.contributorDepartment of Applied Biology and Chemical Technology-
dc.creatorWang, X-
dc.creatorLv, C-
dc.creatorFeng, J-
dc.creatorTang, L-
dc.creatorWang, Z-
dc.creatorLiu, Y-
dc.creatorMeng, Y-
dc.creatorYe, T-
dc.creatorXu, Z-
dc.date.accessioned2015-10-13T08:27:53Z-
dc.date.available2015-10-13T08:27:53Z-
dc.identifier.issn1660-3397en_US
dc.identifier.urihttp://hdl.handle.net/10397/25071-
dc.language.isoenen_US
dc.publisherMDPI AGen_US
dc.rights© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.rightsThe following publication is available at Wang, X.; Lv, C.; Feng, J.; Tang, L.; Wang, Z.; Liu, Y.; Meng, Y.; Ye, T.; Xu, Z. Studies toward the Total Synthesis of Itralamide B and Biological Evaluation of Its Structural Analogs. Mar. Drugs 2015, 13, 2085-2104://dx.doi.org/10.3390/md13042085en_US
dc.subjectBiological studyen_US
dc.subjectCyclodepsipeptideen_US
dc.subjectItralamide Ben_US
dc.subjectStructural analogsen_US
dc.subjectTotal synthesisen_US
dc.titleStudies toward the total synthesis of itralamide B and biological evaluation of its structural analogsen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage2085en_US
dc.identifier.epage2104en_US
dc.identifier.volume13en_US
dc.identifier.issue4en_US
dc.identifier.doi10.3390/md13042085en_US
dcterms.abstractItralamides A and B were isolated from the lipophilic extract of Lyngbya majuscula collected from the eastern Caribbean. Itralamide B (1) showed cytotoxic activity towards human embryonic kidney cells (HEK293, IC50 = 6 £gM). Preliminary studies disapproved the proposed stereochemistry of itralamide. In this paper, we will provide a full account of the total synthesis of four stereoisomers of itralamide B and the results derived from biological tests of these structural congeners.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationMarine drugs, Apr. 2015, v. 13, no. 4, p. 2085-2104-
dcterms.isPartOfMarine Drugs-
dcterms.issued2015-
dc.identifier.scopus2-s2.0-84928538616-
dc.identifier.pmid25871289-
dc.identifier.rosgroupid2014002072-
dc.description.ros2014-2015 > Academic research: refereed > Publication in refereed journalen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_IR/PIRAen_US
dc.description.pubStatusPublisheden_US
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